College Football Betting

Claim a 50% Welcome Bonus for your first deposit on NCAA Football

2021-22 College Football Bowl Odds Breakdown

It’s time for another year of college football betting here at Bovada Sportsbook – and this year will be unlike any other. Student-athletes are no longer being barred from receiving compensation for their name, image and likeness (NIL) rights, which has started something of a feeding frenzy for the top prospects in the game. Plus, on top of the remaining COVID-19 restrictions, the 2021-22 NCAA Division I FBS season will see transfer players become automatically eligible, as well as an added emphasis on taunting penalties. 

This also might be the last year we see the Oklahoma Sooners and Texas Longhorns in the Big 12. They’ve accepted an offer to join the SEC by 2025, leaving the other Power 5 conferences scrambling to catch up. It’s all part of a larger power grab by ESPN, owners of the SEC Network, who appear bent on creating their own “Super League” of college football. Not coincidentally, the SEC stands to benefit the most if the College Football Playoff is expanded to 12 teams, which is currently being negotiated.

College Football Playoff Odds: The Favorites

As if the SEC weren’t already powerful enough. They’re the home of last year’s CFP champions, the Alabama Crimson Tide, who ran the table at 13-0 (9-4 ATS) to win their sixth title under head coach Nick Saban. And once again, the Crimson Tide start the new season in first place on the NCAA football odds board at Bovada Sportsbook. Here are the top five favorites as we go to press:

Alabama Crimson Tide (+250)

College football betting is all about the head coach – and Saban has a lot on his plate this year with much of his talent, including QB Mac Jones, receivers DeVonta Smith and Jaylen Waddle, and RB Najee Harris, moving on to greener pastures, as have several key members of the offensive line. Bryce Young is Alabama’s latest starting quarterback; he’ll be working with a new offensive co-ordinator in Bill O’Brien, who replaces Steve Sarkisian after the latter took the head coaching gig with the Longhorns.

Clemson Tigers (+375)

Tigers head coach Dabo Swinney has an even bigger challenge ahead of him: Replace both QB Trevor Lawrence and RB Travis Etienne. Believe it or not, Clemson’s offense could be even better this year with DJ Uiagalelei under center. And their defense should be better still, with nine returning starters and a wealth of new recruits ready to make up for last year’s injury-plagued campaign.

Georgia Bulldogs (+550)

The Bulldogs have been stuck behind Alabama in the SEC pecking order for quite a while now. Their chances in 2021 depend heavily on quarterback JT Daniels, the talented transfer from USC who will finally get a crack at a full season in Atlanta after recovering from a torn ACL. Daniels will be surrounded by ample talent in the backfield and on the offensive line. Head coach Kirby Smart has also assembled yet another top-flight defense on the other side of the ball.

Ohio State Buckeyes (+600)

After spending much of the past two seasons at or near the top of Bovada’s college football odds board, the Buckeyes are taking a small step back this year. Head coach Ryan Day will have fewer players from Urban Meyer’s regime to work with – none more important than QB Justin Fields, who’s now with the Chicago Bears. Day will choose a new quarterback from a strong list of candidates including CJ Stroud, Quinn Ewers, Jack Miller and Kyle McCord. One or more of them should step forward and shine. Whether Ohio State’s defense can hold up its end is another matter entirely.

Oklahoma Sooners (+700)

The Sooners might be the best value on the board. The Big 12 has been focused on offense for a while now, with OU head coach Lincoln Riley famously churning out quarterbacks Baker Mayfield, Kyler Murray and Jalen Hurts (via Alabama). Riley’s latest charge is Spencer Rattler, who should be even better this season after a solid effort in 2020. But it was their improvements on defense that kept Oklahoma in the title hunt last year, and most of those players will be back in 2021. The Sooners’ front seven could be the difference between playing in another Big Six bowl and winning the CFP National Championship Game in Indianapolis on January 10.

For more information on college football betting, check our our comprehensive NCAAF Football Guide below. Then check the odds and get ready for the greatest NCAAF betting experience you’ll find anywhere, right here at Bovada Sportsbook.

College Football Lines

NCAA Football Week 2 Odds

September 2, 2021 - 8 p.m. ET


No. 4 Ohio State -14 (-115)
Minnesota +14 (-105)

September 3, 2021 - 6 p.m. ET


No. 10 North Carolina -5.5
Virginia Tech +5.5

September 4, 2021 - 12 p.m. ET


No. 2 Oklahoma -26.5 (-115)
Tulane +26.5 (-105

September 4, 2021 - 12 p.m. ET


No. 19 Penn State +4.5 (-105)
No. 12 Wisconsin -4.5 (-115)

September 4, 2021 - 3:30 p.m. ET


No. 1 Alabama -19
No. 14 Miami Florida +19

September 4, 2021 - 3:30 p.m. ET


No. 17 Indiana +3 (-105)
No. 18 Iowa -3 (-115)



Join Now and Claim Your Bonus

September 4, 2021 - 4:30 p.m. ET


No. 23 UL Lafayette +8 (-105)
No. 21 Texas -8 (-115)

September 4, 2021 - 5 p.m. ET


Fresno State +20.5
No. 11 Oregon -20.5

September 4, 2021 - 5 p.m. ET


San Jose State +14 (-105)
No. 15 USC -14 (-115)

September 4, 2021 - 7:30 p.m. ET


No. 5 Georgia +3 (-105)
No. 3 Clemson -3 (-115)

*Odds as of August 29, 2021

Join now and claim your NCAA football bonus in the Bovada SportsbooK!