The Arizona Cardinals (4-4 SU, 2-6 ATS) are having a nightmare 2017 season, but they can take a big step towards the playoffs with a win Thursday night over the visiting Seattle Seahawks (5-3 SU, 3-5 ATS). Kick-off is at 8:25 PM ET on NBC, with Seattle laying 6.5 points on the NFL lines at press time. The Cardinals have lost both quarterbacks Carson Palmer and running back David Johnson for extended periods, leaving them vulnerable in the NFC West. However, the Seahawks have had problems of their own, and safety Earl Thomas (hamstring) sat out their early-week practices after missing last Sunday’s loss to Washington.

Here are some of the other key matchups on the Week 10 NFL odds board, all times Eastern:


Sunday: New Orleans Saints at Buffalo Bills (1 PM, FOX)

Wide receiver Kelvin Benjamin is expected to make his debut for the Bills (5-3 SU, 5-2-1 ATS) as they make a push for the postseason. The Saints (6-2 SU and ATS) are 3-point road favorites on what should be a chilly afternoon at the former Ralph Wilson Stadium, with temperatures in the mid-40s at kick-off.


Sunday: Dallas Cowboys at Atlanta Falcons (4:25 PM, FOX)

Even though running back Ezekiel Elliott may or may not have his suspension delayed another week, the Cowboys (5-3 SU and ATS) have opened as 3-point road dogs against the defending NFC champs. Wide receiver Julio Jones is iffy for the Falcons (4-4 SU, 2-6 ATS) after suffering a high-ankle sprain last week and skipping Wednesday’s practice.


Sunday: New England Patriots at Denver Broncos (8:30 PM, NBC)

The Broncos (3-5 SU, 2-5-1 ATS) will give Brock Osweiler the start on Sunday Night Football, hoping to recapture the same magic that led them to victory over New England (6-2 SU, 4-4 ATS) in 2015. The Patriots are holding firm as 7.5-point road favorites.


Monday: Miami Dolphins at Carolina Panthers (8:30 PM, ESPN)

Despite quarterback Jay Cutler returning to the lineup last week and performing well, Miami (4-4 SU, 3-3-2 ATS) opened as a 9-point road dog for Monday night’s matchup preview with the Panthers (6-3 SU, 5-4 ATS), who were victorious over Atlanta in their first game after trading Benjamin to the Bills.


*Odds as of November 9, 2017